Our Science

Abstracts and Publications

Select A2 Bio Scientific Publications

Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers

Wang X, Sandberg M, Martin A, et al. Journal of Immunotherapy : October 2021.

Extensive Functional Comparisons Between Chimeric Antigen Receptors and T-cell Receptors Highlight Fundamental Similarities

Wang X, Martin A, Negri K, et al. Molecular Immunology : October 2021.

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Design of TCR Structural Variants That Retain or Invert the Normal Activation Signal

Mock JY, Oh J, Yi J, et al. ImmunoHorizons : May 1, 2021.

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Re-examination of MAGE-A3 as a T-cell Therapeutic Target

Martin A, Wang X, Sandberg M, et al. Journal of Immunotherapy : April 2021.

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HLA-A*02:01-directed Chimeric Antigen Receptor/Forkhead Box P3-engineered CD4+ T cells Adopt a Regulatory Phenotype and Suppress Established Graft-versus-host Disease

Martin A, Daris M, Johnston J, et al. Cytotherapy : February 2021.

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Engineered T-cells Directed at Tumors with Defined Allelic Loss

Hamburger A, DiAndreth B, Cui J, et al. Molecular Immunology : December 2020.

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A Multivariate, Quantitative Assay that Disentangles Key Kinetic Parameters of Primary Human T Cell Function In Vitro

Huang GL, Nampe DP, Yi J, et al. PLoS ONE : November 2020.

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Structure-function Relationships of Chimeric Antigen Receptors in Acute T-cell Responses to Antigen

Xu H, Hamburger A, Mock JY, et al. Molecular Immunology : October 2020.

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Cancer T-cell Therapy: Building the Foundation for a Cure

Kamb A, Go W. F1000 Research : November 2020.

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Single variable domains from the T cell receptor β chain function as mono- and bifunctional CARs and TCRs

Oh J, Warshaviak D, Mkrtichyan M, et al. Scientific Report : November 2019.

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A Powerful, Precise Targeting System Controlled by Tumor Deletions Transforms CEA and MSLN CAR-T Cells Into Tumor-Selective Agents

Hamburger A, Xu H, Ando Y, et al. Poster presentation at the Annual Meeting of the Society for Immunotherapy of Cancer (SITC). November 2021.

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BASECAMP-1: An Observational Study to Identify Relapsed Solid Tumor Patients with Human Leukocyte Antigen (HLA) Loss of Heterozygosity (LOH) and Leukapheresis for Future CAR T Cell Therapy

Molina J, Go W, Kopetz S, et al. Poster presentation at the Annual Meeting of the Society for Immunotherapy of Cancer (SITC). November 2021.

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A Computational Approach to Predict Off-target Peptide Selectivity of pMHC Targeting Therapeutics

Warshaviak D, Nampe D, Wang X, et al. Poster presentation at The Essential Protein Engineering & Cell Therapy Summit Virtual. August 2020.

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Tmod™ T cell Therapy Platform Overview

Kamb, A. Interviews conducted at the Annual Meeting of the Society for Immunotherapy of Cancer (SITC). November 2021.

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BASECAMP-1: An Observational Study to Identify Relapsed Solid Tumor Patients with Human Leukocyte Antigen (HLA) Loss of Heterozygosity (LOH) and Leukapheresis for Future CAR T Cell Therapy

Molina J. Oral poster presentation at the Annual Meeting of the Society for Immunotherapy of Cancer (SITC). November 2021.

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Managing Clinical Safety and Toxicity for Improved Patient Outcomes

Go W. Oral presentation at CAR-TCR Summit 2021. August 2021.

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Optimizing Efficiency in Trial Sponsor and Clinician Relationships

Geiger B, Matthews A, Melvin P, et al. Panel discussion at CAR-TCR Summit 2021. August 2021.

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Next-generation Logic-gated Cell Therapy

Go W. Oral presentation at the International Workshop on CAR-T 2021. April 2021.

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Engineered T Cells Directed at Tumors with Defined Allelic Loss

Hamburger A, DiAndreth B, Cui J, et al. Oral presentation at 3rd Cell Therapies and Immunotherapy Conference. October 2020.

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